
TY  - JOUR
A1  - Bishop, Roger 
A1  - Craig, Donald C. 
A1  - Nguyen, Vi T. 
A1  - Scudder, Marcia L. 
T1  - Hydrogen-Bonded Ladders formed by Crystalline Diols
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2002
VL  - 54
IS  - 10
SP  - 637
EP  - 641
KW  - 
UR  - https://doi.org/10.1071/CH01107 
N2  - Certain diol molecules crystallize from solution as unidirectional double-stranded ladders. When these two strands assemble in-phase, a step-ladder arrangement results with the diols linked by (O&#8211;H)4 cycles of hydrogen bonds. Using racemic diol samples, the preferred arrangement has two enantiomerically pure strands of opposite handedness. If the two strands assemble out-of-phase, a staircase-ladder results where the molecules are connected by a hydrogen-bonded (O&#8211;H)n chain. The preferred arrangement contains enantiomerically pure diol molecules surrounding a 21 screw axis. If a racemic diol is used then either the crystals contain both (+)- and (&#8211;)-ladders or, alternatively, self-resolution occurs to yield a conglomerate. New diols (7)&#8211;(9) were synthesized and an X-ray investigation confirmed the prediction that these would produce further double-stranded ladders. These structures revealed new variants of the staircase-ladder where both enantiomers are present, inclusion compounds are formed, or crystallographically independent diol molecules are involved. Manuscript received: 27 August 2001. Final version: 5 November 2001. 
ER  -

