
%0 Journal Article
%A Dyason, Jeffrey C. 
%A von Itzstein, Mark 
%T <emph type="2">Review</emph>: Anti-Influenza Virus Drug Design: Sialidase Inhibitors
%J Australian Journal of Chemistry
%D 2002/04/04
%V 54
%N 11
%P 663-670
%K 
%R https://doi.org/10.1071/CH01173
%U https://www.publish.csiro.au/paper/CH01173 
%X This review will give an overview of the design process behind the development of sialidase inhibitors, which can be used as anti-influenza drugs. Two drugs (Relenza&trade; and Tamiflu&trade;) are already available as prescription drugs and a third (BCX-1812) is currently undergoing third-phase clinical trials. Also, the use of molecular-modelling techniques in the understanding of the mechanism and the prediction of inhibition of this enzyme is reviewed. 
