
TY  - JOUR
A1  - Dyason, Jeffrey C. 
A1  - von Itzstein, Mark 
T1  - <emph type="2">Review</emph>: Anti-Influenza Virus Drug Design: Sialidase Inhibitors
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2002
VL  - 54
IS  - 11
SP  - 663
EP  - 670
KW  - 
UR  - https://doi.org/10.1071/CH01173 
N2  - This review will give an overview of the design process behind the development of sialidase inhibitors, which can be used as anti-influenza drugs. Two drugs (Relenza&trade; and Tamiflu&trade;) are already available as prescription drugs and a third (BCX-1812) is currently undergoing third-phase clinical trials. Also, the use of molecular-modelling techniques in the understanding of the mechanism and the prediction of inhibition of this enzyme is reviewed. 
ER  -

