
%0 Journal Article
%A Varon, D. 
%A Unverzagt, C. 
%A Lioy, E. 
%A Patarroyo, M. E. 
%A Schratt, X. 
%T Synthesis of Mannosyl and Oligomannosyl Threonine Building Blocks found on the <emph type="2">Mycobacterium tuberculosis</emph> 45 kDa MPT 32 Glycoprotein
%J Australian Journal of Chemistry
%D 2002/06/04
%V 55
%N 2
%P 161-165
%K 
%R https://doi.org/10.1071/CH01204
%U https://www.publish.csiro.au/paper/CH01204 
%X Mycobacterium tuberculosis secretes a 45 kDa glycoprotein (MPT 32) carrying mannosylated threonine residues. A general strategy was developed to couple peracetylated mannose, &#945; -(1,2)-linked mannobiose or mannotriose to Fmoc-threonine-benzyl ester. Activation of mannosyl acetates or fluorides by borontrifluoride etherate gave the desired Fmoc-glycosyl amino acid building blocks in good yields. The synthesis leads to stable compounds and can easily be scaled up. 
