
TY  - JOUR
A1  - Bodkin, Jennifer A. 
A1  - Humphries, Edward J. 
A1  - McLeod, Malcolm D. 
T1  - The Total Synthesis of (&#8211;)-Tetrahydrolipstatin
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2003
VL  - 56
IS  - 8
SP  - 795
EP  - 803
KW  - 
UR  - https://doi.org/10.1071/CH03121 
N2  - Careful control during the bromolactonization of &#946;,&#947;;-unsaturated acid (4) was required to regioselectively afford the trans-&#946;-lactone (3) as the major diastereomer. Radical debromination of (3) followed by a three-step sequence of reactions afforded the lipase inhibitor (&#8211;)-tetrahydrolipstatin (1). 
ER  -

