
TY  - JOUR
A1  - Graham, Bim 
A1  - Hearn, Milton T. W. 
A1  - Spiccia, Leone 
A1  - Skelton, Brian W. 
A1  - White, Allan H. 
T1  - Amino Acid Binding to Copper(<emph type="6">II</emph>) in (1,4,7-Triazacyclononane) (<emph type="6">L</emph>-histidine)copper(<emph type="6">II</emph>) Hexafluorophosphate Monohydrate
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2003
VL  - 56
IS  - 12
SP  - 1259
EP  - 1261
KW  - 
UR  - https://doi.org/10.1071/CH03149 
N2  - The synthesis, characterization, and single-crystal X-ray structure determination of [Cu(tacn)(L-His)](PF6)2 . H2O (tacn = 1,4,7-triazacyclononane, L-His = L-histidine) are reported. Spectroscopic studies indicated the formation of the square pyramidal copper(II) complex [Cu(tacn)(L-His)]2+. This was confirmed through structure determination, which also revealed that the distorted square-pyramidal copper(II) coordination sphere is comprised of three nitrogen donors from the tacn macrocycle plus one carboxylate oxygen atom and the primary nitrogen atom from L-histidine. The L-histidine ligand is zwitterionic, with the negative charge on the carboxylate balanced by protonation at one nitrogen atom on the imidazole ring. It binds to the copper centre, forming a five-membered chelate ring, common in amino acid coordination. 
ER  -

