
TY  - JOUR
A1  - Loughlin, Wendy A. 
A1  - Murphy, Michelle E. 
A1  - Elson, Kathryn E. 
A1  - Henderson, Luke C. 
T1  - Synthesis of a Novel Pyrrole Oxazole Analogue of the Insecticide Pirate
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2004
VL  - 57
IS  - 3
SP  - 227
EP  - 232
KW  - insecticides &#8212; synthesis (org.) &#8212; combinatorial chemistry &#8212; pyrrole &#8212; QSAR
UR  - https://doi.org/10.1071/CH03184 
N2  - The pyrrole oxazole 4 is a novel analogue of the broad-spectrum insecticide and miticide pirate 2. The expedient synthesis of pyrrole oxazole 4 in six steps from pyrrole is reported using a synthetic route that could have potential for the solution-phase combinatorial synthesis of analogues. Preliminary biological evaluation of the protected pyrrole oxazole 4 (LD50 1.13 &#956;g mL&#8211;1) and the deprotected pyrrole oxazole 5 (LD50 1.06 &#956;g mL&#8211;1) for potential cytotoxicity was carried out. 
ER  -

