
TY  - JOUR
A1  - Fong, Mei 
A1  - Janowski, Wit K. 
A1  - Prager, Rolf H. 
A1  - Taylor, Max R. 
T1  - A Convenient Synthesis of 2-Substituted Thiazole-5-carboxylates
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2004
VL  - 57
IS  - 6
SP  - 599
EP  - 604
KW  - 
UR  - https://doi.org/10.1071/CH03252 
N2  - The photolysis of ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxylate in acetonitrile containing 0.5% tri- fluoroacetic acid in the presence of thioamides gives moderate (40&#8211;60%) yields of thiazole-5-carboxylate esters. In the absence of trifluoroacetic acid, the intermediate vinyl thioesters can be isolated. That addition of the thioamide to the first formed carbene was, through sulfur, confirmed by X-ray crystal structures of 2-methylthiazole-5-carboxylic acid and a byproduct. 
ER  -

