
TY  - JOUR
A1  - Takagi, Ryukichi 
A1  - Tsuyumine, Shinjiro 
A1  - Nishitani, Hiroko 
A1  - Miyanaga, Wataru 
A1  - Ohkata, Katsuo 
T1  - Stereoselective Synthesis of the Hydrophobic Side Chain of Scyphostatin
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2004
VL  - 57
IS  - 5
SP  - 439
EP  - 447
KW  - 
UR  - https://doi.org/10.1071/CH03298 
N2  - The hydrophobic side chain of scyphostatin was synthesized by a convergent synthetic pathway. The key reactions were the enzymatic asymmetric acetylation of a meso-diol, construction of the C12&#8242;&#8211;C13&#8242; trisubstituted E-olefin moiety by Negishi coupling, and construction of the (2&#8242;E,4&#8242;E ,E,6&#8242;E)-triene moiety by Horner&#8211;Wadsworth&#8211;Emmons olefination. 
ER  -

