
TY  - JOUR
A1  - Lahey, FN 
A1  - Lamberton, JA 
A1  - Price, JR 
T1  - Alkaloids of the Australian Rutaceae. The Structure and Reactions of Acronycidine
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1950
VL  - 3
IS  - 1
SP  - 155
EP  - 171
KW  - 
UR  - https://doi.org/10.1071/CH9500155 
N2  - Acronycidine, C15H15O5N, is shown to be 4,6,7,8-tetramethoxyfurano-(2', 3'-2, 3)-quinoline (VI). It has been degraded to 2,4,5-trimethoxybenzoic acid by a series of reactions, one of which involves the conversion of 3-nitroso-5,7,8-trimethoxy-2,4-dihydroxyquinoline to 4,6,7-trimethoxyisatin by heating with mineral acid. This process appears to be of general application for the conversion of 2,4-dihydroxyquinolines to isatins. Acronycidine readily undergoes oxidative demethylation with either nitric or nitrous acid giving a 1,4-quinone. Quinones are likewise formed from several acronycidine derivatives. 
ER  -

