
TY  - JOUR
A1  - Hancox, NC 
T1  - The Reaction between Acetone and Ammonia. II. Isomeric Oximinoketones related to Diacetoamine
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1950
VL  - 3
IS  - 3
SP  - 450
EP  - 460
KW  - 
UR  - https://doi.org/10.1071/CH9500450 
N2  - The compound 2,2,4,4,6-pentamethyltetrahydropyrimidine hydrate, formed in the reaction between acetone and ammonia at room temperature: is converted by nitrous acid to the 5-oximino derivative in 30 per cent. yield. This oxime is decomposed by acid under mild conditions to give acetone, ammonia, and the salt of 4-amino-4-methyl- 2,3-pentanedione 3-oxime. More vigorous acid treatment of the cyclic oxime, or reaction of the open-chain 3-oxime with boiling dilute acid, causes a migration of the oximino group to the 2 position. Evidence is adduced to show that the 2-oxinze has the &#945;- (anti) configuration, whereas the 3-oxime has the &#946;- (syn) configuration. 
ER  -

