
TY  - JOUR
A1  - Downes, AM 
T1  - Isotope Effect in the Reaction of <sup>14</sup>C-Formaldehyde with Dimedone
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1952
VL  - 5
IS  - 3
SP  - 521
EP  - 529
KW  - 
UR  - https://doi.org/10.1071/CH9520521 
N2  - Formulae for the specific activity of a labelled product at any stage in a reaction which involves an &quot; isotope effect &quot; are discussed. The investigation of isotope effect by isolating a labelled product in consecutive fractions is illustrated by the reaction of 14C-formaldehyde with dimedone. In this reaction the 14C-formaldehyde reacts 0.927± 0.005 times as rapidly as the unlabelled compound at room temperature.   Care must be taken when using dimedone as a derivative for the accurate assay of isotopic formaldehyde if errors due to isotope effect are to be avoided. 
ER  -

