
%0 Journal Article
%A Lamberton, BJA 
%A Price, JR 
%T Alkaloids of the Australian Rutaceae: <I>Medicosma cunninghamii</I> Hook. F
%J Australian Journal of Chemistry
%D 1953/06/01
%V 6
%N 2
%P 173-179
%K 
%R https://doi.org/10.1071/CH9530173
%U https://www.publish.csiro.au/paper/CH9530173 
%X The bark of Medicosma cunninghamii Hook. f. contains approximately 0.06 per cent. of an alkaloid C17H15O3N which has been named medicosmine and shown to be a 2,3-furoquinoline with a dimethylpyran ring fused in either the 5,6- or 6,7-positions (III or IV). It has been degraded to acetone, acetaldehyde, and a phenol which when methylated and oxidized gives 6-methoxy-4-hydroxy-1-methyl-2-quinolone, and 6- and 7-methoxy-4-hydroxy-1-methyl-2-quinolones have been synthesized for comparison. A dihydropyrano-4-methoxy-3-ethyl-2-quinoone is formed by hydrogenolysis of the furane ring. Further examples are reported of the preparation of isatins from 3-nitroso-2,4-dihydroxyquinolines. 
