
TY  - JOUR
A1  - Birch, AJ 
A1  - Massy-Westropp, RA 
A1  - Moye, CJ 
T1  - Studies in relation to biosynthesis. VII. 2-Hydroxy-6-methylbenzoic acid in <I>Penicillium griseofulvum</I> Dierckx
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1955
VL  - 8
IS  - 4
SP  - 539
EP  - 544
KW  - 
UR  - https://doi.org/10.1071/CH9550539 
N2  - The general problem of the biosynthesis of depsides and depsidones is considered. Feeding experiments using sodium acetate isotopically labelled in the carboxyl group have demonstrated that the mould Penicillium griseofulvum Dierckx (Raistrick's strain P68) elaborates 2-hydroxy-6-methylbenzoic acid (VII) by the head-to-tail linkage of acetic acid units in accord with the hypothesis of Birch and Donovan (1953). This demonstration constitutes the first definite support for the hypothesis based on bio- chemical experiments. 
ER  -

