
TY  - JOUR
A1  - Brown, DJ 
A1  - Lyall, JM 
T1  - Pyrimidine reactions. VI. The amination of chloropyrimidines with n-alkylamines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1964
VL  - 17
IS  - 7
SP  - 794
EP  - 802
KW  - 
UR  - https://doi.org/10.1071/CH9640794 
N2  - The aminations of 2-chloro-4,6-dimethylpyrimidine and 4-chloro-2,6-dimethyl- pyrimidine by a series of n-alkylamines (3 moles) have been followed titrimetrically. Between 3° and 70° the rates of these apparently first-order reactions approximately double for each 10&quot; rise. A simple experimental method for predicting optimum conditions of temperature and time for such aminations has been developed. Addition of cuprous chloride has little effect on rates. Fifteen new n-alkylaminopyrimidines have been prepared. 
ER  -

