
TY  - JOUR
A1  - Martin, RJL 
T1  - Acid hydrolysis of acetamide in aqueous acetic acid
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1965
VL  - 18
IS  - 6
SP  - 807
EP  - 819
KW  - 
UR  - https://doi.org/10.1071/CH9650807 
N2  - The hydrolysis of acetamide in acetic acid has been studied over a wide range of reactant and salt concentrations. The various acid-base and ionic association equilibria must be considered in the interpretation of the data. It is shown that the mechanism is a bimolecular reaction between water and the acetamidium ion and that the acetamidium ion pairs and triple ions have no reactivity. Polar substances such as water and acetamide, apart from undergoing reaction, also increase the reaction rate by favouring the dissociation of the ion pairs. Salts exhibit strong ionic strength and ion-pair effects. 
ER  -

