
%0 Journal Article
%A Maclaren, JA 
%A Sweetman, BJ 
%T The preparation of reduced and  S-alkykated wool keratins using Tri-n-butylphosphine
%J Australian Journal of Chemistry
%D 1966/12/01
%V 19
%N 12
%P 2355-2360
%K 
%R https://doi.org/10.1071/CH9662355
%U https://www.publish.csiro.au/paper/CH9662355 
%X When tri-n-butylphosphine is used to reduce the disulphide groups in wool keratin, several different methods can be used for the subsequent alkylation of the thiol groups formed. A novel feature is that in some oases reduction and alkylation can be effected using tri-n- butylphosphine and the alkylating agent acting simultaneously.   S-Alkyl kerateines have been prepared using 11 alkylating agents of various chemical types. By means of such a technique a quantitative and apparently specific conversion of cystinyl residues in wool keratin to S.(2-aminoethyl)cysteinyl residues has been achieved. 
