
%0 Journal Article
%A Jemison, RW 
%T Limitation of cupric bromide for selective side-chain bromination of methyl aryl ketones
%J Australian Journal of Chemistry
%D 1968/01/01
%V 21
%N 1
%P 217-220
%K 
%R https://doi.org/10.1071/CH9680217
%U https://www.publish.csiro.au/paper/CH9680217 
%X 2-Hydroxy-4,6-dimethoxyacetophenone and its acetate undergo nuclear bromination with cupric bromide, and 2,3,4-trimethoxyacetophenone gave w-bromo-2-hydroxy-3,4-dimethoxyacetophenone accompanied by a small yield of 2-hydroxy-3,4-dimethoxyacetophenone and by w-bromo-2,3,4-trimethoxyacetophenone. Formation of the last compound was shown by isolation of w-acetoxy-2,3,4-trimethoxyacetophenone after treatment of the mixture of brominated products with sodium acetate in ethanol. 
