
%0 Journal Article
%A Clark-Lewis, JW 
%A Skingle, DC 
%T Flavan derivatives. XXII. 2'-Substituted flavanones and flavones; aroyl bromides by bromination of aromatic aldehydes
%J Australian Journal of Chemistry
%D 1968/08/01
%V 21
%N 8
%P 2077-2084
%K 
%R https://doi.org/10.1071/CH9682077
%U https://www.publish.csiro.au/paper/CH9682077 
%X Flavanone-2'-carboxylic acid, its methyl ester, and 2'-hydroxymethyl-   flavanone were obtained from 3-o-hydroxyphenaoylphthalide. Bromination of the flavanones gave the corresponding cis-3-bromoflavanones which easily underwent base-catalysed dehydrobromination, and flavone-2'-carboxylic acid and its methyl ester were prepared in this way. Bromination of o-tolualdehyde gave o-toluoyl bromide in a known but hitherto neglected reaction which appears to offer a useful route to aroyl bromides. 
