
%0 Journal Article
%A Angyal, SJ 
%T Conformational analysis in carbohydrate chemistry. I. Conformational free energies. The conformations and &#945; : &#946; ratios of aldopyranoses in aqueous solution
%J Australian Journal of Chemistry
%D 1968/11/01
%V 21
%N 11
%P 2737-2746
%K 
%R https://doi.org/10.1071/CH9682737
%U https://www.publish.csiro.au/paper/CH9682737 
%X The relative free energies of the aldopyranoses in aqueous solution have been calculated, taking non-bonded interaction energies and the anomeric effect into account. It is shown that the calculated free-energy values correctly predict the predominant conformation of the &#945;- and &#946;-pyranose forms of each aldose. The &#945;- to &#946;-pyranose ratios of the aldoses in aqueous solution, calculated from these values, are in reasonable agreement with those determined experimentally. 
