
%0 Journal Article
%A Dalton, LK 
%A Demerac, S 
%A Teitei, T 
%T Synthesis of pyridocarbazoles for anti-tumour studies
%J Australian Journal of Chemistry
%D 1969/01/01
%V 22
%N 1
%P 185-195
%K 
%R https://doi.org/10.1071/CH9690185
%U https://www.publish.csiro.au/paper/CH9690185 
%X Cyclodehydration in orthophosphoric acid of the azomethines of 3- formyl-carbazoles and aminoacetals has yielded 5-methyl- (IId), 3,5,11- trimethyl-(11b), 3,5,9,11-tetramethyl-(IIc), and 5,7,10,11-tetramethyl- 6H-pyrido[4,3-b]carbazoles (IIa). In the same way &#947;-carboline and 6,9- dimethyl-&#947;-carboline were obtained from the azomethines of 3-formyl- and 3-formyl-4,7-dimethyl-indole. A Doebner reaction with 3-amino-2- methylcarbazole, acetaldehyde, and pyruvic acid yielded 1-carboxy-3,5- dimethyl-7H-pyrido[2,3-c]carbazole (VIIIb) from which was derived the methyl ester (VIIIc) and 3,5-dimethyl-7H-pyrido [2,3-c]carbazole (VIIIa). 
