
%0 Journal Article
%A Richards, EL 
%T Imidazoles from the reaction of periodate-oxidized polysaccharides with ammonia
%J Australian Journal of Chemistry
%D 1970/05/01
%V 23
%N 5
%P 1033-1037
%K 
%R https://doi.org/10.1071/CH9701033
%U https://www.publish.csiro.au/paper/CH9701033 
%X Periodate-oxidized amylose reacts with aqueous ammonia to give imidazole and 4(5)-(2-hydroxyethyl)imidazole while periodate-oxidized dextran gives imidazole and 4(5)-methylimidazole. Laminarin after periodate oxidation gives only traces of imidazoles with ammonia. A mechanism is proposed for the formation of these imidazoles from periodate-oxidized polysaccharides. The nature of the imidazoles formed is specific to the linkage in the parent polysaccharide and hence provides a basis for a micro method for linkage analysis. 
