
%0 Journal Article
%A Deady, LW 
%A Shanks, RA 
%A Campbell, AD 
%A Chooi, SY 
%T The synthesis of some substituted methyl pyridinecarboxylates. II. Methyl 4-substituted picolinates, methyl 5-substituted picolinates, and methyl 5-substituted nicotinates
%J Australian Journal of Chemistry
%D 1971/02/01
%V 24
%N 2
%P 385-392
%K 
%R https://doi.org/10.1071/CH9710385
%U https://www.publish.csiro.au/paper/CH9710385 
%X General methods are described for the synthesis of three series of substituted methyl pyridinecarboxylates from readily available starting materials. Methyl 4-X-picolinates and methyl 5-X-picolinates (X = NO2, Br, MeO, Me2N) are prepared from 2-picoline via 4-nitro-2-picoline N- oxide and 2-amino-5-nitropyridine respectively. Methyl 5-X-nicotinates (X = Br, MeO, Me2N) are prepared from 5-bromonicotinic acid. Preparations of methyl 4-methylpicolinate and methyl 5-methylnicotinate from the corresponding lutidines and methyl 5-methylpicolinate from 2-amino-5-methylpyridine are described. 
