
TY  - JOUR
A1  - Savige, WE 
T1  - Isolation and identification of some photo-oxidation products of tryptophan
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1971
VL  - 24
IS  - 6
SP  - 1285
EP  - 1293
KW  - 
UR  - https://doi.org/10.1071/CH9711285 
N2  - When an aerated aqueous solution of tryptophan at pH 6-9 is irradiated by visible light in the presence of a photosensitizing dye, N?- formylkynurenine is usually a major product. However, a similar irradiation in dilute ammonia at pH 8-9 gives mainly 4-(2-amino-2- carboxyethyl)quinazoline, a new amino acid; formyl-kynurenine 1s shown not to be an intermediate in the photoreaction. Tryptophan methyl ester and 2-methyltryptophan give photoproducts analogous to those of tryptophan. On the other hand, N-acetyltryptophan and indole-3- propionic acid give the formylkynurenine analogue either in the absence or presence of ammonia, no quinazoline being detected. 
ER  -

