
%0 Journal Article
%A Pojer, PM 
%A Rae, ID 
%T Synthesis of 2-Benzamido-2-mercaptopropanoic acid from 4-Methyl-2-phenyl-2-oxazolin-5-one
%J Australian Journal of Chemistry
%D 1972/08/01
%V 25
%N 8
%P 1737-1749
%K 
%R https://doi.org/10.1071/CH9721737
%U https://www.publish.csiro.au/paper/CH9721737 
%X The structures of the dimers of N-substituted pyruvamides are confirmed to be the pyrrolidinones (6). 4-Chloro-4-methyl-2-phenyl-2-oxazolin-5-one reacts with a-toluenethiol to give a thiol ester which can be converted into 2-benzamido-2-benzyl-thiopropanoic acid. Reaction of the chlorooxazolinone with thioacetic acid gives 4-acetylthio-4-methyl-2-phenyl-2-oxazolin-one which is converted into 2-benzamido-2-mercaptopropanoic acid. The mercapto acid is oxidized by iron(111) chloride-ether to a mixture of disulphides. 
