
TY  - JOUR
A1  - Brown, RFC 
A1  - Butcher, M 
A1  - Fergie, RA 
T1  - The formation of nitriles by pyrolysis of N-substituted chloroacetamides
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1973
VL  - 26
IS  - 6
SP  - 1319
EP  - 1326
KW  - 
UR  - https://doi.org/10.1071/CH9731319 
N2  - Pyrolysis of chloroacetamides RNHCOCH2Cl at 780-850°C/0.1-0.4 mm with short contact time gives nitriles RCN in 45-60% yield (R = phenyl, o- tolyl, p-tolyl, benzyl, or cyclohexyl). A mechanism is proposed involving the formation of the iso-nitrile RNC, formaldehyde, and hydrogen chloride. N-Chloroacetylbiphenyl-2-amine gives biphenyl-2- carbonitrile (45%) and phenanthridine (15%). 
ER  -

