
%0 Journal Article
%A Walker, WR 
%A Guo, JM 
%A Li, NC 
%T The interaction of H<sup>+</sup>, Zn<sup>2+</sup>, and Cu<sup>2+</sup> with adenine and guanine
%J Australian Journal of Chemistry
%D 1973/11/01
%V 26
%N 11
%P 2391-2399
%K 
%R https://doi.org/10.1071/CH9732391
%U https://www.publish.csiro.au/paper/CH9732391 
%X The interactions of H+, Zn2+, and Cu2+ with adenine and guanine have been investigated by N.M.R. studies in dimethyl sulphoxide (Me2SO). The compounds Zn(adenine)HCl3, Zn(guanine)HCl3, (adenine)HCl, (adenine)2HCl, (guanine)HCl,H2O and (guanine-H)2[ZnCl4]4H2O have also been prepared and studied in Me2SO. The last compound as well as (adenine)2HCl have not been reported previously. N.m.r. spectra are concentration-dependent and also depend upon the hydrogen ion activity. This work has shown that there is little correlation between solid state structures and interactions in solution and, further, that selective line broadening by the para- magnetic Cu2+ ion is not unequivocally diagnostic of the binding site in these systems. 
