
TY  - JOUR
A1  - Broxton, TJ 
A1  - Deady, LW 
A1  - Williamson, PRA 
T1  - The rates of basic methanolysis of some N-Alkyl-p-nitroacetanilides and 4-(N'-Alkylacetamido)pyridines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1974
VL  - 27
IS  - 5
SP  - 1053
EP  - 1057
KW  - 
UR  - https://doi.org/10.1071/CH9741053 
N2  - Rate constants for the basic methanolysis of CH3CONRAr compounds (R=H,Me,Et,Pri; Ar = p-NO2C6H4, 4-pyridyl), and derived activation parameters are reported. There is a close parallel between the effects of the nitro and aza groups on activation energies and entropies foreach R group. The order of reactivity within the R groups is H < Me > Et > Pri. From a consideration of the activation parameters it seems likely that the lower reactivity of the H-compounds is due to the energetically unfavourable breakdown of strongly hydrogen-bonded structures during methanolysis of these compounds. 
ER  -

