
%0 Journal Article
%A Davis, M 
%A Deady, LW 
%A Homfeld, E 
%T Rates of N-methylation of N-methylpyrazole, isothiazole and isoxazole and their 2,1- and 1,2-benzologues
%J Australian Journal of Chemistry
%D 1974/06/01
%V 27
%N 6
%P 1221-1225
%K 
%R https://doi.org/10.1071/CH9741221
%U https://www.publish.csiro.au/paper/CH9741221 
%X The rates of quaternization of N-methylpyrazole, isothiazole and isoxazole and of their 2,l- and 1,2-benzologues with methyl iodide in dimethyl sulphoxide and with dimethyl sulphate are reported. All compounds quaternized at 33º and a number of new compounds were isolated. The order of reactivity in each series is NMe > S > O. Benzofusion was shown to be rate-diminishing with one exception. 2,l-Benzisoxazole reacted faster than did isoxazole and the reason for this behaviour is discussed. 
