
TY  - JOUR
A1  - Frahn, JL 
A1  - Illman, RJ 
T1  - Synthesis of 6-Methoxy-2-methyl-1,2,3,4-tetrahydro-&#946;-carboline
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1974
VL  - 27
IS  - 6
SP  - 1367
EP  - 1369
KW  - 
UR  - https://doi.org/10.1071/CH9741367 
N2  - A convenient, larger-scale preparation of 6-methoxy-2-methyl-l,2,3,4-tetrahydro-&#946;-carboline, an alkaloid occurring in the pasture grass, Phalavis tuberosa L., is described. DL-5-Methoxytryptophan is condensed with formaldehyde and the product, DL-6-methoxy-1,2,3,4-tetrahydro-&#946;-carboline-3-carboxylic acid, treated with dichromate to form 6-methoxy-&#946;-carboline. The methiodide of this base is reduced with borohydride to the required alkaloid in c.60% overall yield. 
ER  -

