
%0 Journal Article
%A Khalil, AM 
%A Abd, El-Gawad II 
%A Hammouda, M 
%T The action of arylamines on some substituted 2-Thiazolin-5-ones
%J Australian Journal of Chemistry
%D 1974/09/01
%V 27
%N 9
%P 2035-2039
%K 
%R https://doi.org/10.1071/CH9742035
%U https://www.publish.csiro.au/paper/CH9742035 
%X The heterocyclic ring in 2-aryl-4-arylmethylene- and 4-arylmethylene-2-benzylthio-2-thiazolin-5-ones is readily opened by the action of primary aromatic amines in acetic acid containing a catalyticamount of sodium acetate with the formation of 1,2-diaryl-4-arylmethylene-2-imidazolin-5-ones and of 3-aryl-5-arylmethylene-2-thiohydantoins respectively. 4-Benzylidene-1-(p-chloropheny1)-2-phenyl-2-imidazolin-5-one was also obtained by the cyclization of the anilide of &#945;-(p-chlorothiobenzamido)-&#946;-phenylacrylic acid under the same reaction conditions. A possible reaction mechanism is postulated. 
