
TY  - JOUR
A1  - Elix, JA 
T1  - 2'-O-Methylphysodic acid and hydroxyphysodic acid: two new depsidones from the lichen <I>Hypogymnia billardieri</I>
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1975
VL  - 28
IS  - 4
SP  - 849
EP  - 858
KW  - 
UR  - https://doi.org/10.1071/CH9750849 
N2  - Two new depsidones, 2?-O-methylphysodic acid and hydroxyphysodic acid, have been identified as minor constituents of the lichen Hypogymnia billardieri (Mont.) R. Filson. The structure of 2?-O-methylphysodic acid was established by chemical interconversions. The overall substitution pattern of this depsidone was confirmed by methylation with excess diazomethane, whereupon methyl 4,2?,4?-tri-O- methylisophysodate was obtained. Further, a direct comparison showed that this metabolite was dissimilar from 4-O-methylphysodic acid which has been isolated previously.     The structure of hydroxyphysodic acid followed from the analytical data, spectroscopic properties and chemical interconversions. This compound is biogenetically unique, since it is the first depsidone isolated in which the basic orcinol nucleus has undergone further hydroxylation. 
ER  -

