
%0 Journal Article
%A Dewar, MK 
%A Johns, RB 
%A Kelly, DP 
%A Yates, JF 
%T Cross-linking of amino acids by formaldehyde. <sup>13</sup>C N.M.R. spectra of model compounds
%J Australian Journal of Chemistry
%D 1975/04/01
%V 28
%N 4
%P 917-924
%K 
%R https://doi.org/10.1071/CH9750917
%U https://www.publish.csiro.au/paper/CH9750917 
%X The use of 13C N.M.R. for the identification of the site of cross- linking of amino acids by formaldehyde has been evaluated by use of model compounds, such as 2,4-dimethylphenol for tyrosine. The 13C chemical shifts of the formaldehyde-derived methylene carbons occur within the range 50-60 p.p.m. downfield from Me4Si. Estimated shifts in lysine-lysine and tyrosine-glutamine cross-linked systems fall just outside this region. The 13C spectra of a number of related phenols, amines and protected amino acids are also reported. 
