
%0 Journal Article
%A Davis, M 
%A Homfeld, E 
%A McVicars, J 
%A Pogany, S 
%T The chemistry of 2,1-benzisothiazoles. IX. The reaction of 3-chloro-substituted 2,1-benzisothiazoles with nucleophiles and the preparation of(2,1-Benzisothiazol-3-yl)acetic acid
%J Australian Journal of Chemistry
%D 1975/09/01
%V 28
%N 9
%P 2051-2055
%K 
%R https://doi.org/10.1071/CH9752051
%U https://www.publish.csiro.au/paper/CH9752051 
%X 3-Chloro-2,1-benzisothiazole (2; R = H, R? = Cl) and 3,5-dichloro-2,1- benzisothiazole (2;R,R? = Cl) react readily with nucleophiles, and yield 3-substituted products. Acid hydrolysis of one such product, ethyl (2,1-benzisothiazol-3-yl)cyanoacetate (2; R = H, R? = CH(CN)CO2Et),affords (2,1-benzisothiazol-3-yl)acetic acid (2; R = H, R? = CH2CO2H), an auxin analogue. 
