
TY  - JOUR
A1  - Clark-Lewis, JW 
A1  - Cox, DP 
T1  - Flavonoid intermediates for the synthesis of mopanol trimethyl ether[<I>trans-trans</I>-7,7',8'-Trimethoxyisochromano(4',3':2,3)chroman-4-ol]
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1976
VL  - 29
IS  - 1
SP  - 191
EP  - 201
KW  - 
UR  - https://doi.org/10.1071/CH9760191 
N2  - Preparation of a number of intermediates for the synthesis of (±)-mopanol trimethyl ether is described, together with exploratory reactions with model compounds, and especially with 7-methoxyflavanone-2'-carboxylic acid. 7-Methoxyflavan-4-ol, the initial product from reduction of 7-methoxyflavanone-2'-carboxylic acid with complex metal hydrides, was found to undergo facile dehydration to a novel intramolecular dibenzyl ether [the cyclic ether (19)*]. It was noted that the methoxymethyl group, which may be used as a protecting group for phenols, did not survive the conditions of methylation with dimethyl sulphate and potassium carbonate in acetone. 
ER  -

