
TY  - JOUR
A1  - Davis, M 
A1  - Hugel, HM 
A1  - Lakhan, R 
A1  - Ternai, B 
T1  - Investigation of ring and nitrogen inversion in N-Methyl-1,2,3,4-tetrahydroisoquinoline by dynamic N.M.R. methods
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1976
VL  - 29
IS  - 7
SP  - 1445
EP  - 1448
KW  - 
UR  - https://doi.org/10.1071/CH9761445 
N2  - &#916;G? for the overall ring and nitrogen inversion barriers in N-methyl-1,2,3,4-tetrahydroisoquinoline has been found to be 35.2 kJ/mol in vinyl chloride, and 50.2 kJ/mol in aqueous solution. Both measurements are believed to reflect the height of the nitrogen inversion barrier. The difference is attributed to hydrogen bonding in the aqueous solution. At low pH anomalous inversion rates were obtained. 
ER  -

