
TY  - JOUR
A1  - Dilli, S 
A1  - Pillai, DN 
T1  - The N-alkylation of some barbiturates and other acidic drugs
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1976
VL  - 29
IS  - 8
SP  - 1769
EP  - 1782
KW  - 
UR  - https://doi.org/10.1071/CH9761769 
N2  - The synthesis of a number of new N,N'-dialkyl barbituric acids is reported. The compounds are ethyl hexobarbital, the diethyl derivatives of secobarbital and cyclobarbital, the chloroethyl derivatives ofmephobarbital and hexobarbital, and the bis(chloroethy1) derivatives of barbital, cyclobarbital, secobarbital, butobarbital and secbutobarbital.In addition, several new N-alkylated derivatives of some common anticonvulsant drugs are included. These are ethyl glutethimide, the chloroethyl derivatives of ethosuximide, glutethimide, peganone, mephenytoin and diphenylhydantoin. Infrared, N.M.R., mass spectral and gas chromatographic retention data are given. 
ER  -

