
TY  - JOUR
A1  - Calder, IC 
A1  - Creek, MJ 
T1  - Reactions of N-acetoxyphenacetin: an <I>in vitro</I> model for the metabolism of phenacetin
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1976
VL  - 29
IS  - 8
SP  - 1801
EP  - 1808
KW  - 
UR  - https://doi.org/10.1071/CH9761801 
N2  - The solvolysis reactions of N-acetoxy-4'-ethoxyacetanilide in the presence of nucleophiles under neutral conditions and at low pH yield p-benzoquinone, 3'-substituted 4'-hydroxyacetanilides and 2'-substituted 4'-ethoxyacetanilides. The product ratio is dependent on the nature of the nucleophile and the pH. This type of reaction accounts for many of the minor metabolites of phenacetin. 
ER  -

