
%0 Journal Article
%A Franke, F 
%A Guthrie, RD 
%T t-Butyldimethylsilyl ethers of sucrose
%J Australian Journal of Chemistry
%D 1977/03/01
%V 30
%N 3
%P 639-647
%K 
%R https://doi.org/10.1071/CH9770639
%U https://www.publish.csiro.au/paper/CH9770639 
%X The usefulness of the t-butyldimethylsilyl group as a blocking group in carbohydrate chemistry has been demonstrated and its selectivity towards primary hydroxyl groups, in the absence of imidazole, shown by preparation of derivatives of methyl &#945;-D-glucopyranoside and sucrose. Methyl &#945;-D-gluco-pyranoside was converted into methyl 6-O-t- butyldimethylsilyl-a-D-glucopyranoside in almost quantitative yield, and sucrose to 6,1?,6?-tri-O-t-butyldimethylsilylsucrose in good yield. In the presence of excess sucrose, a mixture of 6?-O-t- butyldimethylsilyl-, 6,6?-di-O-t-butyldimethylsilyl- and 6,1?,6?-tri-O- t-butyldimethylsilyl-sucroses was formed. 
