
TY  - JOUR
A1  - Chaudhry, IA 
A1  - Clezy, PS 
A1  - Diakiw, V 
T1  - Chemistry of pyrrolic compounds. XXXVI. Some aspects of the chemistry of 2'-hydroxypropionate porphyrins: new syntheses of harderoporphyrin trimethyl ester, 'S-411 porphyrin' trimethyl ester and related compounds
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1977
VL  - 30
IS  - 4
SP  - 879
EP  - 895
KW  - 
UR  - https://doi.org/10.1071/CH9770879 
N2  - The 2?-hydroxypropionate porphyrins (1h) and (2g) were obtained by sodium borohydride reduction of the corresponding keto esters. Dehydration of (1h) and (2g) led to the acrylate esters (1b) and (2b) respectively; fragmentation of both the hydroxyl and carboxyl functions in (1h) and (2g), by way of a cyclic intermediate, furnished the vinylporphyrins (1a) and (2a) respectively. The synthesis of the 2?- hydroxypropionate porphyrin (9a), a possible biogenetic precursor of protoporphyrin-IX, was achieved. 
ER  -

