
TY  - JOUR
A1  - Pasaribu, SJ 
T1  - Synthesis of the major encephalitogenic determinant of myelin basic protein and the <sup>13</sup>C N.M.R. of some protected intermediates
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1977
VL  - 30
IS  - 11
SP  - 2533
EP  - 2544
KW  - 
UR  - https://doi.org/10.1071/CH9772533 
N2  - The main encephalitogenic determinant of bovine myelin basic protein (MBP 114-122) has been synthesized through fragment condensation of tetrapeptide, Boc-Phe-Ser-Trp-Gly-OH, and penta-peptide, H-Ala- Glu(OBzl)-Gly-Gln-Lys(N&#949;-Cbz)-Obzl. It was observed that the benzyl ether protecting group of the serine side chain was not removed during catalytic hydrogenation (Pd/C-H2) of the tetrapeptide, Boc-Phe- Ser(OBzl)-Trp-Gly-OBzl. 13C N.M.R. spectra of some other intermediates are discussed. 
ER  -

