
%0 Journal Article
%A Gainsford, AR 
%A Sargeson, AM 
%T Stereoselective and regioselective condensation reactions of coordinated aminoacetone
%J Australian Journal of Chemistry
%D 1978/08/01
%V 31
%N 8
%P 1679-1688
%K 
%R https://doi.org/10.1071/CH9781679
%U https://www.publish.csiro.au/paper/CH9781679 
%X Treatment of cis-[Co(en)2(NH2CH2R)(NH2CH2COCH3)]3+ ions (R = H, Me, CH2Br, Ph, p-C6H4Cl) with base leads to imine complexes where the coordinated aminoacetone has reacted with a bound monoamine RNH2 or an ethylenediamine moiety. The product distribution appears to be determined by the relative acidity of the monoamine and the ethylenediamine amine centres; condensation is preferred at the most acidic site. Reduction of the imine group in these complexes with BH4- ion leads to new complexes of the type [Co(en)2(NH2CH2CH(Me)NHCH2R)]3+ and [Co(en)(NH2CH2CH2NHCH(Me)CH2NH2)(NH2CH2R)]3+ in which the reduced ligand is synthesized stereospecifically. 
