
TY  - JOUR
A1  - Deady, LW 
A1  - Stillman, DC 
T1  - Mechanisms for the acetylation of aminopyridines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1978
VL  - 31
IS  - 8
SP  - 1725
EP  - 1730
KW  - 
UR  - https://doi.org/10.1071/CH9781725 
N2  - Rates of acetylation of aminopyridines and some ring methyl-substituted derivatives, with acetic anhydride in acetone at 36&#176;, are reported. The results indicate that rate-determining acetylation is directly at the amino nitrogen for all 2- and 3-aminopyridines studied. Reaction through a ring N-acetyl intermediate occurs for 4-aminopyridine but the presence of a 2-methyl substituent blocks this pathway. 
ER  -

