
%0 Journal Article
%A Christie, RM 
%A Rickards, RW 
%A Watson, WP 
%T Microbial transformation of cannabinoids. I. Metabolism of (&#8211;)-&#916;<sup>9</sup>-6a,10a-<I>trans</I>-Tetrahydrocannabinol by <I>Chaetomium globosum</I>
%J Australian Journal of Chemistry
%D 1978/08/01
%V 31
%N 8
%P 1799-1807
%K 
%R https://doi.org/10.1071/CH9781799
%U https://www.publish.csiro.au/paper/CH9781799 
%X Chaetomium globosum isolated from Cannabis sativa plant material converts (-)-&#916;9-6a,10a-frans-tetrahydrocannabinol (&#916;9-THC) (1a) into a number of metabolic products, which include the 3'-hydroxy, 11-hydroxy and 3',11-dihydroxy derivatives (1c), (1b) and (1d) respectively. The structure of the 3'-hydroxy-&#916;9-THC (1c) has been confirmed by synthesis, whilst the structure of the 3',11-dihydroxy-&#916;9-THC (1d) follows from mass spectroscopic comparison with the 3'-hydroxy and 11-hydroxy derivatives. 
