
%0 Journal Article
%A Black, DSC 
%A Crozier, RF 
%A Rae, ID 
%T Nitrones and oxaziridines. XX. Intramolecular nitrone 1,3-dipolar cycloaddition by substituent interaction: Synthesis and reduction of some tetrahydropyrroloisoxazoles
%J Australian Journal of Chemistry
%D 1978/09/01
%V 31
%N 9
%P 2013-2022
%K 
%R https://doi.org/10.1071/CH9782013
%U https://www.publish.csiro.au/paper/CH9782013 
%X The reactions of C-benzoylnitrones with allylamine afford tetrahydro-5H-pyrrolo[3,4-c]isoxazoles resulting from imine formation and intramolecular 1,3-dipolar cycloadditions. Cycloaddition reactions of the same nitrones with 2-vinylpyridine and N-phenylallylamine afford 5-substituted isoxazolidines in the normal way. Reduction of the imine bond in the tetrahydropyrroloisoxazoles can be achieved by catalytic hydrogenation or sodium borohydride, and, in the case of an N-phenyl derivative, N-O bond cleavage also occurs. 
