
%0 Journal Article
%A Pasaribu, SJ 
%A Brophy, GC 
%T Carbon-13 N.M.R. studies of some &#946;-adrenergic agents
%J Australian Journal of Chemistry
%D 1978/12/01
%V 31
%N 12
%P 2629-2634
%K 
%R https://doi.org/10.1071/CH9782629
%U https://www.publish.csiro.au/paper/CH9782629 
%X Carbon-13 chemical shifts of some beta-adrenergic agents of disubstituted phenylaminoethanol derivatives have been measured. It was observed that the ortho-substituent to the alcohol side chain exerted an upfield shift on the methine carbon of the aminoethanol group, whereas the methyl carbons of isopropylamine were found to be magnetically non-equivalent. It was also found that the methylene and methine carbons of the alcohol side chain of 1-isopropylamino-3- naphthyloxy-propan-2-ol (propranolol) were shielded at a similar magnitude as the 2,5-disubstituted phenyl-aminoethanol derivatives. 
