
TY  - JOUR
A1  - Pasaribu, SJ 
A1  - Brophy, GC 
T1  - Carbon-13 N.M.R. studies of some &#946;-adrenergic agents
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1978
VL  - 31
IS  - 12
SP  - 2629
EP  - 2634
KW  - 
UR  - https://doi.org/10.1071/CH9782629 
N2  - Carbon-13 chemical shifts of some beta-adrenergic agents of disubstituted phenylaminoethanol derivatives have been measured. It was observed that the ortho-substituent to the alcohol side chain exerted an upfield shift on the methine carbon of the aminoethanol group, whereas the methyl carbons of isopropylamine were found to be magnetically non-equivalent. It was also found that the methylene and methine carbons of the alcohol side chain of 1-isopropylamino-3- naphthyloxy-propan-2-ol (propranolol) were shielded at a similar magnitude as the 2,5-disubstituted phenyl-aminoethanol derivatives. 
ER  -

