
TY  - JOUR
A1  - Jacobsen, NW 
A1  - McCarthy, BL 
A1  - Smith, S 
T1  - N-Aminopyrimidines: The Isomerization of 1-Aminobarbituric Acids to 2-(5-Oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl) Aliphatic Acids
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1979
VL  - 32
IS  - 1
SP  - 161
EP  - 165
KW  - 
UR  - https://doi.org/10.1071/CH9790161 
N2  - 1-Aminobarbituric acid undergoes a facile isomerization in aqueous acid to 2-(5-oxo-4,5-dihydro-lH-l,2,4-triazol-3-yl)acetic acid which in turn can be decarboxylated to give 3-methyl-1H-1,2,4- triazol-5(4H)-one. The isomerization reaction is shown to be a general one, adaptable to the synthesis of oxotriazolyl aliphatic acids and their decarboxylated products. A reaction mechanism for the isomerization is proposed. 
ER  -

