
TY  - JOUR
A1  - Deady, LW 
A1  - Finlayson, WL 
A1  - Korytsky, OL 
T1  - Steric Effects in Forward and Reverse Menschutkin Reactions of Some Pyridines, Quinolines and Thiazoles
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1979
VL  - 32
IS  - 8
SP  - 1735
EP  - 1742
KW  - 
UR  - https://doi.org/10.1071/CH9791735 
N2  - The effects of ortho alkyl substituents on the rates of methylation of pyridine and demethylation of N-methylpyridinium iodides are compared (some quinolines are included as 'substituted pyridines'). For monosubstituted compounds, substituent steric effects are twice as important in the methylation (forward) reaction as in the demethylation reaction. In contrast, the ratio is 3 : 1 for disubstituted compounds, because the substituent effects are additive in the reverse reaction but greater than additive in the forward reaction. Some thiazole results are also reported and, here, steric effects on the forward reaction are small while no steric acceleration of the reverse reaction is evident. 
ER  -

