
%0 Journal Article
%A Brown, DJ 
%A Grigg, GW 
%A Iwai, Y 
%A McAndrew, KN 
%A Nagamatsu, T 
%A Heeswyck, Rv 
%T Purine Analogues as Amplifiers of Phleomycin. V. Thioethers of Several Heterocyclic Systems with One or Two Rings
%J Australian Journal of Chemistry
%D 1979/12/01
%V 32
%N 12
%P 2713-2726
%K 
%R https://doi.org/10.1071/CH9792713
%U https://www.publish.csiro.au/paper/CH9792713 
%X Thioethers, appropriate for testing as amplifiers of phleomycin against in vitro cultures of Escherichia coli, are prepared via corresponding thiones in the purine, imidazo[4,5-b(and 4,5-c)]pyridine, pyrazolo[3,4-d]pyrimidine, quinazoline, benzothiazole, benzoxazole, pyrimidine, imidazole, thiazoline, 1,2,4-triazole, s-triazolo[4,3-c(and 1,5-c)]pyrimidine, oxazolo[4,5-b]pyridine, quinoline and 1,3,5-triazine series. Structures are confirmed by N.M.R. spectra. Biological activities are tabulated and discussed in terms of structure. 
